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KMID : 1037020150040010039
Medical Lasers; Engineering, Basic Research, and Clinical Application
2015 Volume.4 No. 1 p.39 ~ p.44
Successful Treatment of Refractory Melasma Using Invasive Micro-Pulsed Electric Signal Device
Choi Moon

Choi Seo-Hee
Kang Jin-Soo
Cho Sung-Bin
Abstract
Treatment of facial melasma refractory to low-fluence Q-switched Nd:YAG laser (LFQSNY) and topical lightening agents (TLA) is a challenge. The objective of this study was to investigate the safety and efficacy of an additional invasive micro-pulsed electric signal device (IMPES) for treatment of melasma refractory to LFQSNY/TLA. Five female patients (Fitzpatrick skin type III?IV) with refractory facial melasma were treated using IMPES added to their baseline of LFQSNY/ TLA treatment. Four to seven treatments were administered at 1-week intervals. The power levels ranged from 3 to 5, depth 1.2 mm to 1.7 mm, and single pass. Photographs were taken at the beginning and 1 week after the last treatment. At the last treatment, assessments showed greater than 50% clinical improvement in melasma in all five patients. Follow-up interviews were conducted at the 8th week. No recurrence was reported during the follow-up at 8 weeks. No significant adverse effects were noted. Addition of IMPES to LFQSNY/TLA is a safe and effective treatment for refractory melasma.
KEYWORD
Invasive micro-pulsed electric signal device, Melasma, Nd:YAG, Topical bleaching agent
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